Nail in the coffin
"A nail in someone or something's coffin" is used when someone has made another mistake or bad decission, leading him/her towards a certain failure. For example, if in the office Mary has made a few mistakes in her tasks, and then in the Xmas party she gets drunk and dances on top of a table in front of everyone, someone may say: - "That's another nail in Mary's coffin" - (as in, she is getting closer to getting fired).
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With over 300 shops, Oxford Street and its vicinity is one of the main high-street shopping areas in London. As long as the day, it starts in Marble Arch, passing through Oxford Circus until its end at Tottenham Court Road.
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